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Where appropriate, further investigation, such as testing glutathione status or DHFR genetic variants, may help explain why some individuals respond differently to folic acid and identify when alternative forms of folate may be beneficial

However, the research unambiguously shows that dietary supplementation with spermidine, whether through food rich in spermidine or as a pure compound supplementation, mediates health-beneficial effects 9,113

Chen, X.-F., Wang, L., Wu, Y.-Z., Song, S.-Y., Min, H.-Y., & Yang, Y

US Pharm 47(6):2326 Derbyshire E, Maes M (2023) The role of choline in neurodevelopmental disordersa narrative review focusing on ASC, ADHD and dyslexia

Robinson NE, Robinson AB