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Myeloid cells, particularly neutrophils and monocytes, play a central role in initiating and sustaining vascular inflammation in SLE (212215)

N-acetylcysteine and sulodexide reduce the prothrombotic effect of uremic serum on the venous endothelial cells

By enhancing NRF2s function, it may be possible to strengthen the skin barrier in AD, reducing the susceptibility to irritants and allergens, and thereby mitigating inflammation