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This gets much worse with age, as the accumulation of toxins and cumulative damage of oxidative stress take their toll on the body

People have been studying glutathione for decades, but its not easy to monitor noninvasively. Noninvasive monitoring of glutathione has proved difficult because the biomolecule is diluted nearly three orders of magnitude once it enters the bloodstream, and it is rapidly consumed by other organs and cleared quickly by the kidneys

170 VicarioM.CieriD.ValleseF.CatoniC.BarazzuolL.BertoP.et al (2019)

However, in the human body there are also present redox-active metals such as iron, which is the most abundant transition metal in healthy humans

These trials should also prioritize the development of specific biomarkers to monitor treatment responses and assess drug efficacy in clinical settings