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Each of these eight nutritional family members plays a unique but connected role: Thiamine (B1) : Converts food into usable energy (ATP) and maintains nervous system health [5] Riboflavin (B2) : Regulates metabolism and supports energy production

NAD+ activates sirtuins (particularly SIRT1 and SIRT3), which are NAD-dependent deacetylases that directly suppress NF-kB transcriptional activity