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These findings support the observation, sometimes disputed, that inorganic sulfates are readily absorbed and excreted in urine, in spite of the osmotic effects that they can generate and which lead to their use as laxatives [11,41]

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Women with type 2 diabetes have been found to have higher risks of infertility and miscarriage, as well as lower chances of viable pregnancy and childbirth, compared with non-diabetic women, and not all these differences are explained by obesity or PCOS

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In plain terms, that flagged them for safety-data concerns and effectively stopped licensed compounding pharmacies from preparing them