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doi: 10.3390/antiox12020416 499 SabadashkaMHertsykDStrugaa-DanakPDudekAKanyukaOKucharskaAZet al

Especially in those who are genetically predisposed, oxidative stress strengthens the relationship between environmental factors and the early stages of autoimmune condition

Consequently, mitophagy is primarily regulated indirectly in PDAC by targeting factors such as mitochondrial integrity, mitochondrial dynamics, autophagosome formation, and autolysosome formation [16] (Fig