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Hinzu kommen die Schwche der Leber (Cholinesterase vermindert) und Stauungen der Entgiftung ber die Galle (alkalische Phosphatase erhht)

According to The Cancer Genome Atlas (TCGA) data, 78% of GBM cases present with mutations in the p53 pathway (103), including direct mutations in the p53 gene (in secondary GBM) and a loss of the INK4A/ARF (CDKN2A) gene locus, PTEN mutations and EGFR amplification/loss (in primary GBM) (104)

While randomized controlled trials are certainly needed, the lack of toxicity and low cost (less than $3 for a tube of 1%2% menthol backrub at any drugstore) make this an attractive option

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These findings were confirmed by the histopathological examination, which elucidated the effect of EMPA on restoring cell integrity and alleviating neuronal damage in the hippocampal areas after PTZ administration