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Conditions of reduced oxygen lead to the accumulation of the alpha subunits (HIF), HIF1 and HIF2, which assemble into the active form with its constitutively expressed counterpart, HIF1

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Saunders et al., 2018), while PC activity was also shown to be more than twice as high in cultured astrocytes than in cultured neurons ( Humans also possess a brain-specific GLUD1 paralog called glutamate dehydrogenase 2 (GLUD2) that is expressed more highly in astrocytes than neurons (Nissen et al., 2017)

Under the presumed conditions of thermodynamic normality, the pH values convey distinct meanings: a pH of 7 is synonymous with neutrality, while a pH falling below 7 is indicative of acidity, and a value above 7 is suggestive of alkalinity

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