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For example, RTA is unique transcription factor

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P.GajewskiA.et al

Linus Pauling Institute, Oregon State University

Finally, we tested if longevity extension by reduced rDNA transcription engages a conserved transcription factor SKN-1/Nrf2 with known roles in protective mechanisms such as mitochondrial biogenesis 45 , oxidative stress response 48 , and lipid metabolism 38