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Models testing for the relationship between muscle FF and LFI showed significant associations for right and left paravertebral muscles in the trunk (= 0.42 [95%CI=0.15,0.7], p=0.005 and = 0.48 [95%CI=0.02, 0.10], p=0.016 respectively) and right and left VL muscles in the thigh (= 0.29 [95%CI=0.03, 0.52], p=0.027 and = 0.23 [95%CI=0.03, 0.44], p=0.026 respectively) (Figure 3a)

This leads to numerous effects such as: increased membrane rigidity decreased activity of membrane-bound enzymes (e.g

Elendu C, Elendu RC, Enyong JM, Ibhiedu JO, Ishola IV, Egbunu EO, Meribole ES, Lawal SO, Okenwa CJ, Okafor GC, Umeh ED, Mutalib OO, Opashola KA, Fatoye JO, Awotoye TI, Tobih-Ojeanelo JI, Ramon-Yusuf HI, Olanrewaju A, Afuh RN, Adenikinju J, Amosu O, Yusuf A (2023) Comprehensive review of current management guidelines of chronic kidney disease