Console L, Scalise M, Tonazzi A, Giangregorio N, Indiveri C
Is our diet acidic or alkaline
CJC-1295 with DAC: Long-Acting Through Albumin Binding CJC-1295 with DAC (Drug Affinity Complex) adds a maleimidopropionic acid group that enables reversible albumin binding: Drug Affinity Complex (DAC) modification covalent attachment to plasma albumin Dramatically extended half-life approximately 6-8 days in research models Albumin binding similar in concept to metabolic peptide fatty acid conjugation though chemically different The DAC modification transforms CJC-1295 from a minutes-half-life compound into a days-half-life compound

Disclosure of interest: Kseniia Manysheva: nothing to disclose E-Posters - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.04 - STROKE COMPLICATIONS P2565 - ESOC25-2282 ASSESSING THE QUALITY OF VTE PROPHYLACTIC DEVICE USAGE FOR STROKE PATIENTS AT LEEDS GENERAL INFIRMARY: AN AUDIT AND RE-AUDIT Rohid Zamani 1,2 , Daniel McWilliams 1 , Sameer Limaye 1 1 Leeds General Infirmary, Leeds Teaching Hospitals National Health Service Trust, Leeds, United Kingdom, 2 George Eliot Hospital, Nuneaton, United Kingdom Background and Aims: Intermittent pneumatic compression devices (IPCs) and geko devices are used to reduce the risk of VTE in patients who have suffered an acute stroke
Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha