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Description

In RTK-mediated RAS signaling, the mTORC1 pathway is activated via MAPK/ERK and its effector p90RSK through the RTK RAS MAPK/ERK p90RSK cascade, further resulting in the phosphorylation of TSC2

Clin Sci 132:12431252

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In our current in vitro study, MitoQ, a mitochondria specific antioxidant (known for peroxynitrite and superoxide scavenging) has been included for the first time as there exists no previous data on such study