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Autoimmune illnesses can produce persistent inflammation, which can exacerbate oxidative stress

The removal of the kanamycin cassette was verified by colony PCR using k1, k2 and gene specific primers (Table 3)

606 By activating autophagy and inhibiting ferroptosis, rapamycin reduces the loss of dopamine neurons in the substantia nigra and improves behavioral symptoms in PD model mice, suggesting that the mutual regulation of ferroptosis and autophagy may provide therapeutic targets for drug therapy of PD