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Funding This work was supported by the Outstanding Youth Science Fund of Chongqing Municipal Science and Technology Bureau (CSTB2023NSCQ-JQX0033), Chongqing Municipal Health Commission (2023jstg012), Army Medical University (2022XL004, ZXAIZD001)

This review aimed to explore the molecular mechanisms underlying APAP-induced liver injury, particularly inflammasome activation, and evaluate the current and emerging therapeutic strategies

3 * Setria is made via an innovative fermentation process that results in a pure form of glutathione that: Helps regenerate oxidized Vitamin C back to its active form* Supports glutathione-dependent enzymes crucial for detoxification within the body* Assists glutathione S-transferases in the safe elimination of toxins* Aids the detoxification of xenobiotics in the liver* Backs better immune response* Promotes healthy aging by contributing to the bodys antioxidant defenses and glutathione levels that naturally decline with age* Setria is made in Japan by Kyowa Hakko Bio Co., Ltd

doi: 10.1016/j.psj.2022.102189 109 Al-KhalaifahHSIbrahimDKamelAEAl-NasserAAbdelwarithAARoushdyEMet al

MR is based on the random allocation of alleles from parents to offspring, ensuring that the formation of fertilized eggs and fixed genotypes remain unaffected by the disease