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Introduction Sickle cell disease (SCD) is a genetic disorder that disproportionally affects people of African descent ( Intravascular hemolysis, a critical contributor to vaso-occlusive crises---the principal pathological manifestation of SCD---refers to the destruction of red blood cells (RBCs) within the blood vessels (Yusuf et al., 2010

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Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), and clay-colored stools

This system achieves thrombus-targeted delivery through interactions between platelet membrane proteins and thrombotic sites, particularly via Annexin V binding to phosphatidylserine exposed on activated platelet membranes

Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles