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HA integrity has also been shown to critically modulate TGF--driven fibroblast differentiation, as enzymatic fragmentation suppresses -smooth muscle actin (-SMA) and collagen type I expression, emphasizing the importance of balanced HA turnover for proper ECM remodeling and scar resolution [9]

B12 deficiency is one of the most treatable causes of cognitive and neurological decline, but only if you catch it before the damage becomes permanent

If one or more of the three are low, I want to know whether that deficiency is translating into elevated homocysteine levels, because that changes how I think about the patients overall clotting risk

doi: 10.3390/nu3030370