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Description

Biosynthesis of lipoic acid via unsaturated fatty acids

These AgNPs induced G2/M phase cell cycle arrest and activated caspase-3 in KB oral cancer cells, achieving an IC50 of 58.64 g/mL

This process is accompanied by excessive ROS generation

Its design illustrates a radical peptidomimetic : only two amino acid residues (Tyr-Ile) are preserved from the native peptide, flanked by non-peptide acyl chains to cross biological barriers