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Chemical reduction of menadione Menadione and menadiol (300 M) were incubated with 1 mM DTT or 10 mM GSH in water at room temperature for 5 min, and then measured by absorbance spectrum ranging from 200 to 450 nm by using a Spectra Max M2e (Molecular Devices)

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Parenteral and oral dosages, and intramuscular and intranasal dosages produce similar pharmacokinetic profiles (2)