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10.1073/pnas.1701536114 Proc

2012 Aug;1823(8):1295-305

Specifically, prolonged antioxidant supplementation is not recommended since it can disrupt endogenous antioxidant levels and interfere exercise-induced adaptation, thereby blunting body's defense against oxidative stress (Peternelj and Coombes, 2011

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As a result, concentrating exclusively on single targets or pathways may not fully capture the true mechanisms underlying TCM and could lead to a limited or even inaccurate understanding of its efficacy