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2.3.2.1 KYN By depleting Trp, IDO is known to inhibit the function of immune cells, including T lymphocyte proliferation, and to potentially downregulate the inflammatory response

Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates

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stems revealed to exert significant amelioration in APAP-induced apoptosis, inflammation, and oxidative stress through regulation of mitogen-activated protein kinase and caspase-3 signaling pathway ( Tournefortia sarmentosa Lam