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pylori in GI malignancies and anaerobic bacterial species like Fusobacterium and Bacteroides fragilis in CRC are the two examples of direct connection ( Candida albicans and Fusobacterium nucleatum ( 2 Gut microbiome and micronutrients in cancer According to the statistical data from the International Agency for Research on Cancer (IARC), factors such as poor diet, lifestyle, smoking alongside overpopulation and aging, are expected to significantly escalate the worldwide burden of cancer by 2030 ( 2.1 Interactions between fat soluble vitamins, gut microbiome and cancer 2.1.1 Vitamin A The human GI tract provides a hospitable environment for a diverse array of microbes

Despite the wealthy research regarding B12 and PA, doctors will often refuse to prescribe more than one shot every few months

It doesn't require specific timing relative to meals, though many researchers administer it on a consistent weekly schedule (e.g., every Sunday evening) to simplify adherence tracking

A deficiency in Se can result in reduced antioxidant protection, impaired immune system function, and various disorders related to the cardiovascular, muscular, endocrine, or neurological systems, with an increased risk of certain cancers, cognitive impairment, and infertility [110]

Effect of riboflavin status on the activity of antioxidant enzymes As expected, some reports have indicated that riboflavin status can affect the activity of antioxidant enzymes including GPx, superoxide dismutase (SOD) and catalase