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In the context of addressing aspects of sarcopenia or age-related impairments in skeletal muscle, 21-22-month-old mice were administered either a regular chow diet or the same diet supplemented with sulforaphane for 12 week ( Bone Sulforaphane has also been proposed to protect against osteoclastic bone destruction in vitro (Luo et al., 2021)

Immunoprecipitation and immunofluorescence assays further indicated that TGF1 treatment enhanced the interaction between ACAT1 and SMAD3/4 within the nucleus (Fig