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The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma

In line with this observation, the pre-administration of DSePA (2 mg/Kg bodyweight) for five consecutive days significantly improved the 30-day survival of mice against the lethal dose (-rays, 10 Gy) of WBI by preventing lipid peroxidation, DNA damage, and apoptosis in the radiosensitive organs like the spleen and small intestine [88, 89]

That reputation comes from the underlying thymosin beta-4 research, which is closely tied to actin regulation and wound healing biology