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More importantly, the NMS of GI dysfunction (i.e., constipation) often appears much earlier in PD patients, predating the onset of motor symptoms by as many as 20 years (Abbott et al., 2001

Existing studies simply showed that the reduced gut Lactobacillus abundance in OA patients was associated with iron overload and chondrocyte ferroptosis

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In certain studies, a high GST expression was associated with a shorter distant metastasis-free and overall survival 21, 22 whereas others had a better outcome

In other words, even patients with very advanced stages of the disease are able to navigate their homes and neighborhoods and will not have to depend on guide dogs or other aids that are commonly associated with total blindness