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Prevalence was also lowest for Black, non-Hispanic individuals in the Midwest, and individuals with a household income of $25,00049,999 in the Northeast

It has previously been shown that immobilised galectin-8 activates Ras leading to increased phosphorylation of ERK1 and ERK2, while addition of the pan-phosphoinositide 3-kinase (PI3K) inhibitor wortmannin nullifies this effect 42

If this finding holds up in larger studies, it could have a major impact on public health. We saw nearly full compliance, which suggests that this is not only a well-tolerated therapy, but one people can realistically stick with, says co-author Martin C

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