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In this study, it was observed that the expression of BSEP, SHP, and FXR was upregulated

Voyvodic PL, Min D, Liu R, Williams E, Chitalia V, Dunn AK, Baker AB

It targets only the pigment without harming the surrounding skin when the proper protocols are observed

Investigating the normal distribution of data was done through the DAgostino & Pearson omnibus normality test

For LC-MS analysis, samples were thawed on ice-water bath, then 40 L of whole blood was injected into 450 L cold extraction solvent comprising of mixture of Acetonitrile:Methanol:Milli-Q water in ratio 40:40:20 according to protocol described in Presterud et al 35