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PMID: 78

doi: 10.1038/s41591-022-01923-y [DOI] [PMC free article] [PubMed] [Google Scholar] 41.Kang C

Gut 53 , 13741384 (2004)

MM patients who progressed after daratumumab treatment had elevated levels of the complement inhibitors CD55 and CD59, in agreement with the hypothesis that CDC represents a major mechanism of action for daratumumab and suggesting a mechanism of resistance to CDC-mediating antibodies