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Cui L, Huang H, Zhang H, Wang X, Qin X, Tu T, Zhang J, Su X, Yu H, Bai Y, Luo H, Yao B, Wang Y (2022) Recombinant expression of hen egg white lysozyme with the assistance of xylanase fusion partner in Pichia pastoris

FIGURE 7 7 Discussion 7.1 Limits of preclinical models and translational relevance While a growing body of preclinical evidence supports the therapeutic potential of redox-targeted antioxidants and stem cellderived EVs in mitigating oxidative stress and restoring ovarian function, significant translational hurdles remain before these strategies can be applied clinically in women

10.3390/ijms251910319 41 KhassafiN.Azami TamehA.MirzaeiH.RafatA.BaratiS.KhassafiN.et al (2024)

This protection appears to be mediated by Akt/PKB and MAPK signalling pathways[366], and it has been suggested that stimulation of this survival pathways may be turned to therapeutic advantage for protection against cell death and progression of nephropathy

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