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ScientificWorldJournal 2012:561823

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The RNAi molecules usually include the short interfering RNAs (siRNAs), the short hairpin RNAs (shRNAs) and the artificial miRNAs, which need to be delivered to the cell via the viral vectors (e.g., adeno-associated viruses) to function as gene silencers (41)

Leqembi, which works by removing a toxic protein called beta amyloid from the brain, is the first Alzheimers treatment proven to alter the course of the fatal, brain-wasting disease