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doi: 10.1016/j.jconrel.2013.09.007 91 DesprsP

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As a result, the concentration and types of ROS generated as byproducts of redox reactions differ between compartments

Reported side effects The side effects reported in trials and research protocols tend to be mild and transient: Common: Injection site reactions: redness, swelling, mild irritation at the injection location Headache: reported in some subjects, typically mild and temporary Mild gastrointestinal discomfort: occasional reports of nausea or upset stomach Less common: Temporary dizziness Slight increases in heart rate Minor liver enzyme elevations in some subjects These effects, when they occur, generally resolve without intervention and don't require discontinuation

Targeting Glutathione Metabolism: Partner in Crime in Anticancer Therapy