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What is 5-amino-1MQ

Nature 396 , 7780 (1998)

[DOI] [PMC free article] [PubMed] [Google Scholar] 1442.Zhang YJ, Xu YF, Liu YH, Yin J, Li HL, Wang Q, Wang JZ

We attempted to antagonise this effect on stability by further increasing the net negative charge of scFvs at a lower pH and by decreasing their pI through fusion of the human influenza hemagglutinin (HA) tag (YPYDVPDYA) with low pI (3.53) and a net negative charge (2.2) to the C-terminus of s3Flag-scFv-A36 or s3Flag-scFv-M4 (Fig