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Postabsorptive subjects completed a glycogen-depleting exercise protocol, then consumed 330ml of one of three drinks, glucose polymer solution, 8g glutamine in 330ml glucose polymer solution, or 8g glutamine in 330ml placebo, and also received a primed constant infusion of [1-13C] glucose for 2h

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A major contributing factor to hippocampal damage is the increase in oxidative stress, which disrupt normal neuronal functioning 56

Mechanistically, Myc drives glutaminolysis by upregulating GLUD1 and induces a concurrent increase in the expression of GLS and SLC1A5 24