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Patients need to be screened for contraindications (pregnancy/breastfeeding, cancer, metabolic diseases, hormone imbalance and certain types of medications)

10.1039/c7bm00652g 73 MaX.WenX.YangX.ZhouD.WuQ.FengY.et al (2018)

Almost all these reactions are catalyzed by GSTs, and there is a specific one in human cells that can cause the conjugation of GSH to HNE at about 100 times faster rate than the non-enzymatic reaction

Glutathione, often referred to as the master antioxidant, is essential for various functions, including detoxification, skin health, immunity, and liver support