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Despite the numerous benefits, the deployment of UDTs faces several challenges, such as the high costs of implementation, data standardization issues, and also raises ethical concerns related to privacy and algorithmic bias

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This is mainly the result of biliverdin and bilirubin formation (24)

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Lactate metabolism is critical for homeostatic axonal maintenance [55], but neurons also participate in the direct uptake of glucose (via GLUT3), which they metabolize primarily through oxidative phosphorylation