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Alternative dilution: Add 5 ml of BAC water final concentration 1 mg/ml (1,000 mcg/ml) preferred for finer dosing in small-animal protocols

It can also cause more pain at the injection site because muscle tissue has more nerve endings than fat

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In contrast, several studies suggested that the activation of ERK and JNK phosphorylates MITF at Ser 73 , which leads to its ubiquitination and degradation, thus subsequently down-regulating melanogenesis (not shown in Figure 3) [26,3941]

After brief aspiration to check for blood vessel puncture, inject slowly over 5-10 seconds