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Despite their clinical prevalence, the molecular mechanisms remain incompletely characterized

Minutoli, L

J Transl Med (2015) 13:303

reported that anisomycin could downregulate the expression of B-cell CLL/lymphoma 2 (Bcl2), CASP8 and FADDlike apoptosis regulator (CFLIP), and myeloid cell leukemia sequence 1 (BCL2-related) (Mcl1), thereby enhancing renal tumor cell apoptosis [12]