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Circadian asthma airway responses are gated by REV-ERB

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References 1 Abdel-TawwabM.WafeekM

Intermittent infusion may be used when there are concerns about the stability of medicine in solution for long periods of time (as is common with continuous infusions), or to enable the administration of medicines which would be incompatible if administered at the same time in the same IV line, for example vancomycin

Similarly, mitophagy enhancers (e.g., urolithin A) and metabolic regulators (e.g., nicotinamide riboside, metformin) have shown promising activity in cellular and animal models, but their therapeutic effects in human PD (mitochondrial dysfunction evolving over decades) are largely unknown [135,136,137,138]