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In the cell, cystine is first reduced to cysteine, and then enters the cell with the help of transporter SLC7A11 to participate in the synthesis of GSH, thus enhancing the activity of GPX4, the main antioxidant enzyme

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Springer Netherlands, Dordrecht, pp 273303 Reddel HK, Bacharier LB, Bateman ED, Brightling CE, Brusselle GG, Buhl R, Cruz AA, Duijts L, Drazen JM, FitzGerald JM, Fleming LJ, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Mortimer K, Pitrez PM, Sheikh A, Yorgancioglu AA, Boulet LP (2022) Global initiative for asthma strategy 2021: executive summary and rationale for key changes

Paul-Henry Koop 1 Jan Clusmann 2 Carolin Schneider 3 Kai Markus Schneider 4 , 1 RWTH Aachen University, 2 RWTH Aachen University Hospital, 3 University Hospital RWTH Aachen, The Perelman School of Medicine, University of Pennsylvania, 4 University hospital RWTH Aachen Background: Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease characterized by immune-mediated destruction of hepatocytes

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