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Zabolinejad N, Molkara S, Bakhshodeh B, Ghaffari-Nazari H, Khoshkhui M (2019) The expression of serotonin transporter protein in the skin of patients with chronic spontaneous urticaria and its relation with depression and anxiety

- After antioxidants neutralize free radicals, they regenerate each other in this chain

Consequently, GSH depletion can be used to trigger cancer cell death [18]

Their research highlighted that ROS modulate key signalling events during capacitation, including the increase in cAMP, PKA activation, phosphorylation of specific substrates, MEK-like protein phosphorylation, and late tyrosine phosphorylation of fibrous sheath proteins, with these processes being regulated by various kinases, including protein kinase C, PKA, and protein tyrosine kinases