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Finally, the hydrodynamic sizes of the nanozyme were measured using DLS, and the sizes appeared slightly larger than those observed under TEM ( Fig

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The fact that mitochondria promotes metabolic plasticity associated with resistance to therapy and the existence of several drug able regulators, proposes this events as promising therapeutic targets in cancer

In a transgenic mouse model of mutant alpha-synuclein (A53T), experiments showed that alpha-synuclein accumulation in astrocytes affected glutamate transport, triggering a rise of extracellular glutamatergic concentrations and excitotoxicity, which further exacerbated damage to dopaminergic neurons (Gu et al., 2010)