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In the treatment with three active ingredients the subjects were administered for 16 weeks daily dosing of 5 grams of hydrolyzed collagen (HC) with 80 mg of vitamin C and 30 mg of hyaluronic acid (triple treatment n = 28)

Moreover, further intervention longer than 1 year should be conducted with a larger sample size to confirm the efficacy of the intervention

10.1155/2013/463595 J