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Description

S.SchousboeA.HeW.LinJ

Selenium and selenoproteins in the brain and brain diseases

Koide and his colleagues successfully developed a noncovalent inhibitor, termed 12VC1, that can highly selectively bind to the active states of KRAS (G12V) and KRAS (G12C) in vivo and in vitro 142

Furthermore, APP/PS1 and Tg4510 mice on a KD for 3 months showed improved locomotor activity, although no improvement in learning or changes in amyloid or tau deposits were detected (8)