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Another small, randomized, double-blind trial in 93 individuals with low vitamin D status found no additional benefit of B-vitamin supplementation (50 mg/day of vitamin B6, 0.5 mg/day of folic acid, and 0.5 mg/day of vitamin B 12 ) on markers of bone health over a one-year period beyond that associated with vitamin D and calcium supplementation

J Altern Complement Med 2006;12:881-5

Encourages Healthy Aging at the Cellular Level Research continues to explore NAD+'s role in supporting DNA repair and healthy cell function

Supplementing helps, but it doesn't fully solve the problem

(Kraus et al., 2014) elucidated that NNMT silencing significantly reduced relative adiposity in mice by approximately 47%