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The antioxidant drug amifostine (Ethyol) has been shown in preclinical and clinical studies to reduce the nephrotoxicity of cisplatin without interfering with antitumor activity (Akbulut 2014

[DOI] [PMC free article] [PubMed] [Google Scholar] 139.Conklin D.J., Haberzettl P., Prough R.A., Bhatnagar A

The physiological consequences of these alterations have not been studied in details but pollutant-induced alterations of the gut bacteria are likely to contribute to their toxicity

This means it attracts and binds water molecules up to 1,000 times its weight in water

Although fatty acid metabolism has also been shown to support CD8+ T memory development (OSullivan et al, 2014), it remains unclear whether CD8+T memory cells share similar mitochondrial alterations