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the increase in fasting glucose in these patients might be explained by a stimulatory effect of glycine on glucagon secretion.45 Glycine supplementation was also associated with significant reductions in systolic blood pressure and plasma markers of oxidative stress.45 Importantly, when 5-g glycine was administered along with 25-g glucose in an oral glucose tolerance test, the subsequent increase in plasma glucose was notably blunted compared to the response to glucose alone