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Description

Increased expression of hepatic Stearoyl-CoA desaturase (SCD)-1 and depletion of eicosapentaenoic acid (EPA) content following cytotoxic cancer therapy are reversed by dietary fish oil

10.1074/jbc.M114.610782 65 McCorvieT

Specifically, the mutation Q141K encoded by the common SNP (single nucleotide polymorphism) rs2231142 reduces urate transport rates by ~50% (half-functional ABCG2) compared to wild-type ABCG2