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Ammonia concentration in the brain is regulated by the mitochondrial glutamate dehydrogenase, which catalyzes the reversible conversion of glutamate to -ketoglutarate and ammonia, using NADH or NADPH as a co-factor (Islam et al., 2010

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Berberine, found in plants like Coptis chinensis , has been shown to have antibacterial effects by intBerberineerfering with bacterial DNA replication and cell membrane integrity (Xiong et al., 2022)