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] (IV;V)), SLR115 ( dvIs67 [ tbb-6p ::GFP+ myo-3p ::dsRed]), SJ4005 ( zcIs4 [ hsp-4 ::GFP] V), SJ4100 ( zcIs13 [ hsp-6 ::GFP]), CF1903 ( glp-1 (e2144) III), GR1373 ( eri-1(mg366) IV ) and MQ1333 ( nuo-6(qm200) I ) strains were obtained from the Caenorhaditis Genetics Center and handled according to standard methods 67

Rather than observing increasing and persistent JNK activation (persistent pJNK), rising ROS levels, peroxynitrite formation, and release of Endo G and AIF, instead they found pJNK decreased over time to undetectable levels, and hepatic necrosis was prevented ( Figure 22 )

By restoring L-Arg levels, these microorganisms synergize with PD-L1 blockade, as L-Arg repletion overcomes T cell exhaustion and enhances the efficacy of checkpoint inhibition (299)

As reported in the previous paragraphs, melatonin is a widespread potent molecule that can reduce cellular damage

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