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I., Garcia-Roman, J., Gomez-Nanez, I

Red beetroot betalains: Perspectives on extraction

However, increasing non-ionic surfactants and cholesterol beyond optimal levels (above 30 mg) led to reduced entrapment efficiency and larger particle sizes in niosomes, likely due to disrupted vesicular structures and potential formation of mixed micelles 56,57

doi: 10.2147/TCRM.S363564

184 But, in a preclinical study on the DMBA-induced rat mammary carcinoma, this enhanced effectiveness of methotrexate was far outweighted by the growth-stimulating effect of 3-day pretreatment with combined insulin/glucose infusions