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Therapies and Models of Citrin Deficiency While the dysfunction of citrin manifests in a complex clinical phenotype across different life stages, therapeutic options remain limited, and no current treatment addresses the underlying metabolic dysregulation comprehensively

CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

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These data indicate that other angiogenic factors such as VEGF could circumvent the FGF blockade

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